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I am a Senior Scienist in computational biology with a broad background in bioinformatics and stochastic processes. This perspective has already made a drastic impact on bioinformatics best practices. I am excited to bring it to industrial research and development, and work with interdisciplinary teams to help change the world of biotech.

Table of contents

General Information

Name Gennady Gorin
Location Emeryville, California
Summary Senior Scientist, Computational Biology at Fauna Bio, building tools for non-model organism omics
Goals Bringing a rigorous mechanistic approach to industry omics research and development

Education

  • 2018 - 2023
    Ph.D.
    California Institute of Technology, Pachter Laboratory
    • Thesis: "Stochastic Foundations for Single-Cell RNA Sequencing"
    • Academic laboratory developing end-to-end, physically informed bioinformatics methods
      • Developing physical theory and scalable stochastic methods for multi-modal single-cell sequencing data
      • Organizing cross-disciplinary, multi-institution collaborations in physics and machine learning
      • Building, training, and leading a subgroup dedicated to addressing gaps in current methods
  • 2013 - 2017
    B.S./B.A.
    Rice University
    • Bachelor of Science in Chemical and Biomolecular Engineering
    • Bachelor of Arts in Chemistry and Asian Studies

Technical Skills

Computation Python (NumPy, SciPy, PyTorch, pandas), MATLAB, bash, CentOS administration
Data analysis bioinformatics (kb, scanpy, velocyto, Monod) for multi-modal single-cell RNA sequencing technologies
Modeling stochastic biophysical modeling, simulation, and inference; variational autoencoder design
Mathematics stochastic processes, partial differential equations, approximation theory

Communications Skills

Interpersonal collaborating in a fast-paced pharma startup, building effective teams for solving problems
Written scientific manuscripts, industry technical reports
Visual data visualization, qualitative illustrations of mathematics and biophysics
Verbal seminar presentations to specialist and non-technical audiences, scripted and unscripted theater
Languages native English and Russian; elementary French and Mandarin

Work Experience

  • 2023 – present
    Senior Scientist, Computational Biology
    Fauna Bio
    • Startup applying hibernation biology discoveries to improve human health
      • Designing computational methods for non-model organism omics
  • 2022
    Data Sciences Co-op
    Celsius Therapeutics
    • Pharmaceutical startup leveraging transcriptomic analyses to develop therapeutics
      • Designed methods to decipher transcriptional mechanisms of disease states for drug discovery
      • Integrated analyses into the company’s cloud computational pipeline for large patient datasets
  • 2017 - 2018
    Research Intern
    Golding Laboratory, Baylor College of Medicine
    • Academic laboratory synthesizing experiments and biophysics to decipher cell biology
      • Designed stochastic simulations and statistical analyses of microbial gene regulation
      • Organized a collaboration at the Xu Laboratory, Shanghai Jiao Tong University, to develop algorithms
  • 2016
    NSF Research Experience for Undergraduates Intern
    Douglas Laboratory, Indiana University
    • Academic laboratory developing virus-like particles as a biotechnology platform
      • Designed, constructed, and modeled a reactor to investigate flow kinetics of encapsulated enzymes
  • 2015
    Future Chemists International Summer Camp Participant
    Lu Laboratory, University of Science and Technology of China
    • Undergraduate-level research and cultural immersion program
      • Synthesized novel palladium nanoparticles and monitored their catalytic activity by gas chromatography
  • 2013 - 2014
    Research Assistant
    Zubarev Laboratory, Rice University
    • Academic laboratory studying nanoparticle applications
      • Synthesized, functionalized, and analyzed gold nanoparticles
      • Closely assisted a graduate student mentor in optimizing synthetic conditions
  • 2012
    Welch Summer Scholar Program Participant
    Smith Laboratory, University of Texas at Dallas
    • High school-level chemistry research program across the University of Texas system
      • Synthesized medical carbon fiber precursors, characterized and presented their performance

Open Source Projects

Presentations and Professional Development

  • 2023
    • American Physical Society March Meeting
      • "Interpretable and tractable probabilistic models for single-cell RNA sequencing", talk
  • 2022
    • Theoretical Biophysics podcast
      • "Modeling bursty transcription", episode
    • Chen Neuroscience Research Building Weekly Seminar Series
      • "Parameterizing models of stochastic transcriptional dynamics with snapshot scRNA-seq data", seminar
    • Cold Spring Harbor Laboratory Systems Biology 2022
      • "Parameterizing models of stochastic transcriptional dynamics with snapshot scRNA-seq data", talk
  • 2021
    • Caltech Chemistry and Chemical Engineering Seminar Day
      • "How should we think about cells?", seminar
    • Gordon Research Conference on Stochastic Physics in Biology 2021
      • "Markov models of RNA transcription and sequencing", poster
    • Society for Industrial and Applied Mathematics Dynamical Systems 2021
      • "Modular and interpretable models of transcriptional noise and splicing", poster
    • Biophysical Society 2021 Annual Meeting
      • "Analysis of Length Biases in Single-Cell RNA Sequencing of Unspliced mRNA by Markov Modeling", poster
  • 2020
    • Cold Spring Harbor Laboratory Genome Informatics 2020
      • "Analysis of Length Biases in Single-Cell RNA Sequencing of Unspliced mRNA by Markov Modeling", poster
    • Biophysical Society 2020 Annual Meeting
      • "Semi-Analytical Methods for RNA Burst Models", poster
  • 2019
    • Caltech Graduate Research Spotlight
      • "RNA velocity and protein acceleration from multimodal single-cell experiments", poster
  • 2018
    • q-bio 2018 Conference
      • "Simulating and Fitting Stochastic Models of RNA Transcription via the Gillespie Algorithm", poster
    • q-bio 2018 Summer School
  • 2017
    • Rice Engineering Design Showcase
      • "Cow Manure to Methanol by Hydrothermal Gasification"
    • Akers Senior Design Competition
      • "Cow Manure to Methanol by Hydrothermal Gasification"
  • 2016
    • Indiana University Materials Symposium
      • "A Flow Reactor Using Catalytic Bulk-Assembled Virus-Like Particles", poster

Pedagogical and Consulting Experience

  • 2019 - 2021
    Teaching Assistant
    Division of Chemistry and Chemical Engineering, Caltech
    • Graded graduate-level chemical engineering thermodynamics courses
  • 2015 - 2017
    Technical Intern
    Houston Asian American Archive, Rice University
    • Researched and proposed solutions for an oral history archive’s website and storage
    • Created a video for university’s celebration of Asian alumni attended by nearly 200 people
  • 2017
    Teaching Assistant
    Department of Bioengineering, Rice University
    • Developed rubrics for and graded an upper-level bioengineering numerical methods course
  • 2014
    Teaching Assistant
    Department of Chemistry, Rice University
    • Graded a sophomore-level Organic Chemistry course

Volunteer Experience

  • 2013 - 2018
    Operations Director/Secretary
    KTRU Rice Radio, Rice University
    • Managed PSA and promotion rotation of an FM college radio station
    • Ensured compliance with FCC regulations
    • Developed budgetary documentation and secured grant funds up to $25,000
    • Hosted a musique concrète radio show
  • 2021
    Proofreader
    Distributed Proofreaders
    • Proofread public domain e-books for Distributed Proofreaders, a non-profit project that produces texts for Project Gutenberg

Awards

  • 2019
    • Caltech Graduate Research Spotlight Second Prize
  • 2014
    • Rice Engineers Week Student Competition Prize Winner
  • 2013
    • Rice Center for Engineering Leadership Liftoff Winner

Scholarships and Honors

  • 2017
    • Dwane Rivers Memorial Scholarship in Chemical Engineering
    • Undergraduate Asian Studies Internship Award for summer internship in Asia
  • 2016 - 2017
    • Louis J. Walsh Scholarship in Engineering
    • T.W. Moore Scholarship, awarded to 5 juniors with highest GPAs in department
  • 2013 - 2017
    • Rice University President's Honor Roll, 6 out of 8 semesters at Rice University